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Doubts abound about a new Alzheimer’s blood test
  + stars: | 2023-10-18 | by ( Judith Graham | ) edition.cnn.com   time to read: +10 min
The Quest Diagnostics blood test, AD-Detect, measures elevated levels of amyloid-beta proteins, a signature characteristic of Alzheimer’s. But Alzheimer’s researchers and clinicians aren’t convinced the Quest test is backed by sound scientific research. Though blood tests for Alzheimer’s are likely to become common in the years ahead, the Alzheimer’s Association said it’s premature to offer a test of this kind directly to consumers. Because the science behind blood tests for Alzheimer’s is still developing and because “patients may not really understand the uncertainty of test results,” Edelmayer said, the Alzheimer’s Association “does not endorse the use of the AD-Detect test by consumers.”Quest’s blood test is one of several developments altering the landscape of Alzheimer’s care in the United States. The bottom line: Before taking a test, “older adults need to ask themselves, ‘Why do I want to know this?
Persons: aren’t, Alzheimer’s, Michael Racke, , there’s, Suzanne Schindler, St . Louis, That’s, ” Schindler, Racke, Meera Sheffrin, , Rebecca Edelmayer, ” Edelmayer, Eric Widera, Dr, Sanjay Gupta, Emily Largent, ’ ”, Munro Cullum Organizations: Health, Diagnostics, Alzheimer’s Association, Quest, University of Michigan, International Conference, Washington University School of Medicine, Senior, Stanford Healthcare, The University of Michigan, FDA, National Institute, Aging, University of California, Get CNN, CNN Health, University, Pennsylvania’s Perelman, of Medicine, HIPAA, University of Texas Southwestern Medical Center, Kaiser Health, KFF Locations: U.S, San Diego, St ., United States, San Francisco
For years, experts have debated what to advise older adults in this situation. Only 27% to 44% of older adults meet these guidelines, according to various surveys. Epidemiologic research suggests that the ideal body mass index (BMI) might be higher for older adults than younger adults. The study’s conclusion: “The WHO healthy weight range may not be suitable for older adults.” Instead, being overweight may be beneficial for older adults, while being notably thin can be problematic, contributing to the potential for frailty. Indeed, an optimal BMI for older adults may be in the range of 24 to 29, Carl Lavie, a well-known obesity researcher, suggested in a separate study reviewing the evidence surrounding obesity in older adults.
Persons: they’ve, , Mitchell Lazar, we’re, John Batsis, Anne Newman, , Carl Lavie, Lavie, , ” Lavie, Newman, you’re, Dinesh Edem, Dennis Kerrigan, Katie Dodd Organizations: CNN, US Centers for Disease Control, Institute for Diabetes, University, Pennsylvania’s Perelman, of Medicine, University of North Carolina School of Medicine, Center for Aging, Health, University of Pittsburgh School of Public Health, BMI, World Health Organization, WHO, University of Pittsburgh, University of North, University of Arkansas, Medical Sciences, Henry Ford Health, Kaiser Health, KFF Locations: , Chapel Hill, New Orleans, University of North Carolina, Michigan
Austin Johnson in August 2019 when his eyes and skin had turned yellow from liver disease caused by years of heavy drinking. Courtesy Austin JohnsonCirrhosis or severe liver disease used to be something that mostly struck people in middle age, or older. “We’re definitely seeing younger and younger patients coming in with what we previously thought was advanced liver disease seen in patients only in their middle age, 50s and 60s,” said Mellinger. Since 2018, Mellinger, and doctors at the Michigan Alcohol Improvement program provide psychiatrists and addiction specialists to patients with liver disease. The yellow color in his skin and eyes — a symptom of severe liver disease — has disappeared.
A study published Wednesday in JAMA Psychiatry found that abortion restrictions may have played a role in some suicide deaths among younger women from 1974 to 2016. The study is the first of its kind to show an association between abortion restrictions and suicide rates among younger women, said Dr. The researchers did not find the same association for older women, he said, suggesting that the increased suicide risk was specific to women directly affected by TRAP laws. Elevated suicide rates in states with more restrictive abortion laws "is cause for clinical concern," he wrote. That research ended in 2016, though, so it's unclear how newer abortion restrictions — such as the Supreme Court decision to overturn Roe v. Wade — have affected suicide rates among younger women.
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